Associate Principal Scientist Resume Sample
Jeffery Ernser
9748 Westley Spurs,
Los Angeles,
CA
+1 (555) 709 5054
Work Experience
Associate Principal Scientist
08/2016
-
PRESENT
Philadelphia, PA
- R&D Work Experience 7+ years
- Work with CRO’s to outsource routine protein expression and production work
- Direct management of 1-4 scientists
- NA Snacks & Confections Ingredient Pipeline Strategy
- Linkage with Procurement to drive supplier strategy
- Drive global linkage to ensure global teams are practicing in-line with the pipeline strategy
- CREW: Collaborate with “sister” regions to share learning’s on productivity programs
R&D Associate Principal Scientist
05/2011
-
04/2016
Philadelphia, PA
- Support category leaders to execute brand productivity 4-2-1’s
- Platform responsibility to support the transition from proof of principle to PDR ready; providing guidance through commercialization leveraging learning’s gained in proof of principle
- Provide oversight and to use innovative approaches to design robust formulations, high throughput screening and manufacturing processes suitable for sterile dosage forms
- Direct the design and performance of studies directed at late stage development and validation of assays and methods supporting Merck’s biologics pipeline and inline products
- Serves as a statistical representative on cross-functional teams for the strategic planning and execution of product development
- Develops individual protocols and statistical analysis plans and independently determines appropriate statistical methodology for analysis
- Prepares oral presentations and written reports to effectively communicate clinical trial results to the project team, Merck Management, regulatory agencies, or individual investigators
- Consults on biomarker aspects of the clinical development strategy to meet scientific and regulatory project goals
- Participates in database design meetings as needed, to ensure that the data evaluated are in high quality and satisfy analysis requirements
Associate Principal Scientist, Engineering
04/2008
-
12/2010
New York, NY
- Collaborates with statistical programming staff to ensure all programs meet analysis requirements, internal standard operating procedures, and external regulatory requirements
- Responds to queries relating to study design, analysis, and interpretation posed by clinical monitors, regulatory agencies, and/or investigators
- Conducts research activities for innovative statistical methods and applications in clinical trial development, especially related to the use of oncology and pharmacogenetic biomarkers
- The assurance of deliverable quality and process compliance
- Membership on departmental strategic initiative project teams such as new statistical computing
- Platform evaluation and development
- Technical/scientific leadership, department representation on cross-functional teams, conducting and interpreting experiments, writing technical reports
- Drive Innovation through technical optimization and creative insight generation on fruit ingredients/elements for Powdered Beverages compositions
Education
Brown University
2004 - 2008
Science's Degree in Statistics
Professional Skills
- Participates in teams focusing on late stage clinical process development, characterization, and validation with line-of-sight for licensure and commercialization.
- Provides technical leadership in the interpretations of trends observed in commercial process monitoring (e.g., statistical process control (SPC) and/or multivariate analyses (MVA)), and for further technical investigations and process changes that seek to drive improvements to yield and/or robustness
- Strong skills in experimental design, mathematical problem solving, critical data analysis/interpretation, statistics, and hands-on computer modeling skills
- Strong molecular biology skills with direct hands-on experience in protein and antibody discovery and engineering as demonstrated by publications/patents
- Strong analytical and communication skills with ability to effectively present scientific findings to project teams
- Excellent communication skills, excellent command of English both written and oral
- Excellent communication and interpersonal skills and ability to negotiate and collaborate effectively
How to write Associate Principal Scientist Resume
Associate Principal Scientist role is responsible for scientific, leadership, interpersonal, analysis, software, programming, collaboration, analytical, technical, design.
To write great resume for associate principal scientist job, your resume must include:
- Your contact information
- Work experience
- Education
- Skill listing
Contact Information For Associate Principal Scientist Resume
The section contact information is important in your associate principal scientist resume. The recruiter has to be able to contact you ASAP if they like to offer you the job. This is why you need to provide your:
- First and last name
- Telephone number
Work Experience in Your Associate Principal Scientist Resume
The section work experience is an essential part of your associate principal scientist resume. It’s the one thing the recruiter really cares about and pays the most attention to.
This section, however, is not just a list of your previous associate principal scientist responsibilities. It's meant to present you as a wholesome candidate by showcasing your relevant accomplishments and should be tailored specifically to the particular associate principal scientist position you're applying to.
The work experience section should be the detailed summary of your latest 3 or 4 positions.
Representative Associate Principal Scientist resume experience can include:
- Strong collaboration and communication skills along and the ability to work well in multidisciplinary teams are essential
- In vivo and in vitro experience and experimental skills in the use of animal models
- Effective leadership, negotiation, influencing, motivational, coordination, and communication skills across a diverse global fast paced organization
- Excellent oral and written communication skills. Ability to communicate complex technical concepts in a simple to understand way
- Experience of solving chemistry-related industrial problems from defining the problem though to validation and communicating output
- Knowledge of crystallography and/or solid-state chemistry and/or solid-state NMR
Education on an Associate Principal Scientist Resume
Make sure to make education a priority on your associate principal scientist resume. If you’ve been working for a few years and have a few solid positions to show, put your education after your associate principal scientist experience. For example, if you have a Ph.D in Neuroscience and a Master's in the same sphere, just list your Ph.D. Besides the doctorate, Master’s degrees go next, followed by Bachelor’s and finally, Associate’s degree.
Additional details to include:
- School you graduated from
- Major/ minor
- Year of graduation
- Location of school
These are the four additional pieces of information you should mention when listing your education on your resume.
Professional Skills in Associate Principal Scientist Resume
When listing skills on your associate principal scientist resume, remember always to be honest about your level of ability. Include the Skills section after experience.
Present the most important skills in your resume, there's a list of typical associate principal scientist skills:
- Excellent verbal and written communication skills, demonstrated creativity, strong interpersonal skills
- Novel publications and excellent oral and written communication skills and organizational skills
- Strong oral and written communication skills. Able to function effectively in a team environment
- Effectively represent the department to key stakeholders, effectively engage and present to staff at all levels, including senior management
- Solid testing and troubleshooting skills able to work independently in electrical lab setting
- Proven team leader with influence and outstanding communication (including presentation) and people skills
List of Typical Experience For an Associate Principal Scientist Resume
1
Experience For R&D Associate Principal Scientist Resume
- Good evidence for delivering on commitments and working collaboratively in
- High level problem solving, and reasoning skills required
- Evidence of creative application of computational approaches to problems in solid-state modeling
- Have strong knowledge in Biologics Laboratory Development AND/OR have gained experience in a Manufacturing Operations background
- Collaborating with biologists to suggest further experiments and validate key findings
2
Experience For Associate Principal Scientist Biologics & Vaccines Resume
- Demonstrated ability in leading, coaching and mentoring technical staff
- Experience developing high-throughput screening assays to analyze protein variants with automated liquid handling
- Experience with manufacturing process development, production, and QC testing of clinical diagnostics is required
- Experience with application of ISO13485, QSR, GMP/GLP, and FMEA/PFMEAs to product design, testing, and manufacturing is required
- Advance NMR crystallography/solid-state NMR modeling support
- Responsible for directing development and validation of laboratory methods and techniques
3
Experience For Associate Principal Scientist, Engineering Resume
- Act as an effective and creative team member in supporting drug discovery projects to meet their objectives
- Hands on experience in animal handling and in vivo techniques
- Highly skilled at representing complex methods/data for the consumption of both senior leadership and bench scientists
- Development of effective data analytics methodologies for process and raw materials (e.g., statistical process control (SPC) and/or multivariate analyses (MVA)
- Developing, optimizing, implementing LC-based assays for recombinant proteins, lipid nanoparticles, conjugate & live-virus-based vaccines
- Understanding of statistical methods, quality control, data reporting and archiving
- Managing lab personnel and testing activity
4
Experience For Associate Principal Scientist Coolers Resume
- Advancing research in molecular modeling to enhance drug discovery and development processes
- Supporting project teams in creating SDTM deliverables for A&R and submission,
- Collaborating with project teams to prepare the CRT submission deliverables including use of Pinnacle 21 Enterprise,
- Partnering with Merck Research Labs (MRL) to provide support for pipeline biologics from phase III through launch
- Collaborating with internal/external partners (Raw material suppliers, external manufacturers etc)
- Coordinating execution of PET tracer - focused studies
- Designing, creating and maintaining databases to host, analyze and share raw and analysis data
5
Experience For Product Development Associate Principal Scientist Resume
- Defining and delivering technological solutions to meet industry demands for the production of recombinant proteins and monoclonal antibodies
- Actively participating on cross-functional manufacturing teams to advance projects goals and deliverables related to process and raw materials
- Presentation of research results to discovery, preclinical and clinical teams, including writing of manuscripts for submission to peer - reviewed journals
- Sustains a culture that promotes employee development through developmental assignments and training. Travel to research and manufacturing sites as required
- Have a deep understanding of manufacturing process as a whole
- Support other departments when technical issues arise in the areas of poultry vaccine manufacturing, testing or performance in the field
- Create preliminary plan for qualification drawing from customer requirements, manufacturing capabilities, and regulatory requirements
- Mentor leaders and scientists on urgency, meeting deadlines, writing appropriate study designs which would include resource requirements and timelines
6
Experience For Associate Principal Scientist Flow Chemistry Resume
- Be instrumental in writing customer facing reports for complaint/failure investigation. Provide technical approval for written customer reports
- Co-authorship of IND, IMPD, and NDA/WMA submissions as well as responding to agency questions and interacting with Health Authorities
- An understanding of criteria determining actionability of data for successful drug discovery
- Enjoy working in a dynamic, challenging, and diverse environment; collaborate well in matrix international team
- Shows flexibility and agility in responding to changing needs across BPDC and Merck.
- Builds talent and group capabilities by influencing and mentoring junior staff members
7
Experience For Associate Principal Scientist Protein Mass Spectrometry Resume
- Act as a leader in the laboratory, driving program and chemistry strategy and execution
- Identify or develop software solutions to realize real-time process monitoring and Advanced Process Control
- Has responsibility for the design and conduct of epidemiology research using large automated database systems
- Deep SME for manufacturing investigations support (Product and process deviations and complex material-related)
- Actively participate on cross-functional manufacturing teams to advance projects goals and deliverables related to process and raw materials
8
Experience For Associate Principal Scientist Bioprocess Formulation & Process Development Resume
- Support for Clinical Trial Applications (CTA’s) in Phase I-III, Product, Registration and Launch (PR&L) filings, and post filing activities
- Independently design and implement various in vitro/ ex vivo assays using a wide range of methodologies
- Provide hands on support in maintaining NMR and lab equipment infrastructure
- Lead problem solving / lessons learned activities
- Use the most appropriate experimental design and problem solving methods
- Provide high content imaging/phenotypic assay and complex cell model development expertise to target biology and drug discovery in broad therapeutic areas
- Collaboration with Imaging Department personnel, drug discovery program team leads, and clinical scientists
- Advance research in molecular modeling to enhance the drug discovery and development processes
9
Experience For Associate Principal Scientist, Immuno Resume
- Explore formulation modeling of API-polymer interactions and peptide-surfactant systems
- Proactively resolves technical challenges to support preventing deviations in unit operations
- Be a recognized expert in field USP and/or DSP operations from working in a cGMP environment
- Expert in leading resolution of multi-disciplinary, cross-departmental technical problems
- Proactively applying newest seperation technology to better characterize complex vaccines
- Responsible for maintaining the highest standards of animal welfare and ethical compliance as well as data integrity
- Deep understanding of pharmacology, physiology and immunology
- Selects the appropriate modelling tools to solve the problem and, if necessary, the correct external partner to build the model / simulation
- Responsible for the end to end generation and delivery of the dairy ingredients pipeline, working with global and regional R&D teams
10
Experience For Associate Principal Scientist Oncology Resume
- A deep understanding of the role of molecular pathways in human disease
- Authors required regulatory and technical documentation according to standard Merck practices
- Understand fruit ingredients properties, functionalities and applications based on Powdered Beverages applications
- Build, execute and recommend plan related to the Fruit Technology platform under the individual responsibility
- Contribute to Global projects and teams on strategic proactive initiatives
- Interpret data, findings or results and define subsequent steps while demonstrating sound scientific know-how and capability to link findings to Business, customers and consumers objectives
- Responsible for technical recommendations and their knowledge sharing to be implemented by Regions
- Guarantee inclusion of new fruit elements technical solutions into Global Ingredient Menu Card
- Generate technical documentation for internal Mondelēz International delivery knowledge base
List of Typical Skills For an Associate Principal Scientist Resume
1
Skills For R&D Associate Principal Scientist Resume
- Strong analytical skills and working knowledge of imaging processing and data analysis programming languages and/or software packages
- Strong analytical skills and working knowledge of imaging processing techniques, data analysis programming languages and / or software tools
- Proven skills in leading scientific teams
- Solid project management skills. An understanding of biology of disease and drug discovery and development
- Excellent project leadership skills in driving for results and innovation
- Fluent in English and excellent writing skills
- Excellent organization, communication, interpersonal, and computer skills
- Strong interpersonal, verbal, and written communication skills and ability to execute in a matrix organization
2
Skills For Associate Principal Scientist Biologics & Vaccines Resume
- Experience in effectively managing analytical development and testing activity at external vendors such as CROs
- A proven track record of problem solving supported by a track record evidenced by a strong publication or patent record
- Strong skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics
- Excellent communication, presentation, analytical and scientific writing skills
- Solid data analytical and problem solving skills, with proficiency in standard scientific software used for data analysis
- In-depth knowledge and understanding of biochemical/biological assays and possess strong scientific & technical leadership skills
3
Skills For Associate Principal Scientist, Engineering Resume
- Critical thinker with strong data analysis skills including application of statistics
- Strong interpersonal and collaboration skills to work in a team - oriented, matrix environment
- Expertise in using computational chemistry software as well as knowledge in scientific computing, and programming skills (e.g. Python, Perl, C, C++, Java)
- Strong hands - on skill on prototyping, board bring - up and troubleshooting down to component level
- Experience identifying, developing, and maintaining effective partnerships with contract research and/or technology organizations
- Prior experience with engineering, expression and purification of proteins using classical techniques is advantageous
- Solid understanding and hands-on experience in upstream process characterization and scale-down model development for cell culture process
- Demonstrated ability to build strong relationships and collaborate with cross functional partners
4
Skills For Associate Principal Scientist Coolers Resume
- Strong computational background and excellent knowledge of modern computational chemistry
- Statistical programming skills (R/MATLAB/SAS)
- Solid experience in using statistical tools (JMP, Spotfire and SIMCA) for data mining, data analysis and modeling
- Interpersonal skills necessary for working in a highly collaborative, cross-functional working environment
- Demonstrated experience leading technical teams, strategic initiatives and/or managing direct reports
- The ability to work effectively with multidisciplinary teams and make impact
- Developing effective data analytics methodologies for process and raw materials including statistical process control and metrics
- Experience in conducting environmental risk assessments including modeling of the environmental exposure and evaluating effects
- Experience developing and running high-throughput screening assays with automated liquid handling
5
Skills For Product Development Associate Principal Scientist Resume
- Experience in training and mentoring team members in analytical and chromatography chemistry in an industrial setting
- Experience in training and mentoring team members in a relevant setting
- Expertise in signal processing and is knowledgeable on controller validation, tuning and optimization
- Experience in equipment programming and maintenance including liquid handlers and small scale column chromatography, i.e. Tecan, FACS Aria and Waters UPLC
- Experience in one or more of the areas of peptide-protein or protein-protein interactions, molecular dynamics, informatics and scripting or protein modeling
- Participates in teams focusing on late stage process development, characterization, and validation with line-of-sight for licensure and commercialization
- Experience in microbiology, synthetic biology, metabolic engineering or natural extracts
6
Skills For Associate Principal Scientist Flow Chemistry Resume
- Hands-on experience leading preclinical small molecule drug discovery projects
- Experience working cross-functionally in a matrix environment
- Experience from drug discovery teams with a track record of working in drug design projects
- Lead formulation hypotheses and design solid experimental plans to prove these, conduct appropriate testing, gather and analyses data
- Experience in representing the analytical functional area on project teams
- Experienced in Next Generation Sequencing and current NGS data analysis tools
7
Skills For Associate Principal Scientist Protein Mass Spectrometry Resume
- Experienced in chromosome spreading and FISH techniques
- Experienced in genome editing with mammalian cells
- Demonstrated hands on expertise of automation and high throughput screening; analysis and interpretation data
- Relevant experience applying design to peptide or peptide-like moieties
- Excellent track record of publications, posters, and speaking engagements
- Experience in bioinformatics and robotic sample handling
8
Skills For Associate Principal Scientist Bioprocess Formulation & Process Development Resume
- Highly skilled in the use and maintenance of Bruker and / or Varian NMR software and hardware including cryoprobes and the application of NMR automation tools
- Experience with management or mentoring of scientific personnel
- Experience with cell culture media manufacturing processes, single use process development, and drug development (small molecule or biologics)
- Experience developing a variety of formulations and processes
- Experience in designing and executing mouse behavioral studies
- Strong working knowledge of primary neuronal and glia cell culture methods
- Experience of working on or leading field trials in remote locations or tropical locations
9
Skills For Associate Principal Scientist, Immuno Resume
- Experience of working in or with soil science or genetic techniques laboratories
- A proven track record demonstrating a well-organized customer focused approach, preferably gained within a drug discovery environment
- Demonstrated ability to adapt personal style to work in international environment
- Experience in fibrosis and/or tissue regeneration in vivo
- Experience with Quality and Regulatory Requirements
10
Skills For Associate Principal Scientist Oncology Resume
- Authoring, reviewing, and editing technical documents to support regulatory filings including technical reports, risk assessments, and CTD sections
- Framing critical drug development questions for optimizing model-based development
- Working knowledge of CMC filing requirements
- Evaluating and developing innovative process technologies, continuous process improvements and post commercial process enhancements to support in-line products
- Understanding and knowledge of industry practices, familiarity with competitors to contribute on design of competitive species research program
List of Typical Responsibilities For an Associate Principal Scientist Resume
1
Responsibilities For R&D Associate Principal Scientist Resume
- Proven relationship builder with outstanding influencing skills, having experience of working with and motivating a remote project team
- Significant data acquisition, analysis, and signal processing skills, including previous experience in using a variety of analysis/reporting tools
- Experience with a matrix environment and ability to effectively collaborate with colleagues from a wide range of disciplines
- Excellent interpersonal, collaboration, and leadership skills
- Programming/Scripting skills (Python/Perl/Shell/etc.)
- Programming skills in Python, Pipeline Pilot, R or related data analysis software packages
- Experience with implementation and monitoring of microbiological food safety programs and good manufacturing practices relevant for microbiological safety
- Hands-on analysis experience with large genetic, genomic, and clinical datasets , with proven record of impact on the drug development process
2
Responsibilities For Associate Principal Scientist Biologics & Vaccines Resume
- Good knowledge of organic chemistry; experience in a medicinal or process chemistry environment is desirable
- Demonstrated ability to communicate scientific findings through a strong publication and presentation record
- Hands-on experience in drug delivery (i.e. Solubilization, nanoparticles, etc.) and solid state phase characterization, salt selection and polymorph evaluation
- Working knowledge of biological assay qualification, validation, and transfer to an cGMP environment
- Working knowledge of Good Laboratory Practices (GLPs)
- Experience in using automated plate-based assay platforms, liquid handling instrumentation, or multi-readout/format plate readers
- Experience in using computational tools for homology modeling, de novo predictions, structure visualization and analysis, protein NMR and crystallography
- Experience in authoring regulatory submissions and associated supporting source documents
3
Responsibilities For Associate Principal Scientist, Engineering Resume
- Experience with digitalization, collection & analysis of “big data”, modeling & programming
- Hands-on experience in developing stable chemically-defined media formulations, and implementing in GMP environment
- Experience in developing high-throughput workflows with automated liquid handling
- Experience in leading or coordinating internal or external discovery teams
- Research and drug discovery working experience in multiple therapeutic areas, including immunology, oncology, cardiovascular and neuroscience
- Good understanding of the regulatory guidelines governing cGMP manufacture is critical
- Experience with modern data mining techniques including ANNs
4
Responsibilities For Associate Principal Scientist Coolers Resume
- Experience in authoring and reviewing CMC regulatory documentation
- Proven understanding of statistics, quantitative data analysis, and data mining
- Experience with mechanistic elucidation of chemical reactions using proper analytical techniques
- Experience in biochemical/biophysical assay development (e.g. radioligand binding, HTRF, and BRET)
- Experience in using HDX-MS for characterization of protein-ligand interactions
5
Responsibilities For Product Development Associate Principal Scientist Resume
- Operations experience in the manufacturing of sterile drug products, at pilot and/or commercial scale
- Strong track record of publications, presentations, and speaking engagements
- Experience in applying statistical analyses to experimental designs and results
- Solid understanding of impact of cell culture medium components on cell culture systems, and under different process conditions
- Experience in applying systems biology tools and high-throughput cell culture methods
- Experience with matrix management and peer to peer coaching
- Hands on experience with advanced analytical techniques including HPLC, UPLC, and other separation techniques is required
- Experience in processing of live virus, vaccines, biologics, and cell culture, fermentation equipment
6
Responsibilities For Associate Principal Scientist Flow Chemistry Resume
- Strong understanding of upstream process characterization or expression system development for vaccines and/or biologics
- Experienced in FACS sorting cell line development
- Experienced in automation and liquid handling equipment
- Supervisory experience of leading 1 – 2 junior scientists or interns
- Automation experience with high-through molecular cloning, protein expression and characterization is desirable
- Experience leading multi-disciplinary teams to deliver on goals
- Experience using analytical instrumentation such as UPLC, HPLC, LC-MS, and GC
7
Responsibilities For Associate Principal Scientist Protein Mass Spectrometry Resume
- Experience working on therapeutic antibody discovery programs
- Experience with process scale-up and technology transfer, moving from laboratory to pilot plant and production scale
- Experience in GCP/GLP and Part 11 SOP writing and/or compliance activities
- Previous experience studying protein kinetics via incorporation of stable isotopes (amino acids, deuterated water) is desirable
- Hands-on experience in clinical development or managing the implementation of biomarker assays in support of drug development
- Hands-on experience practicing LC/MS in a relevant industrial field
- Experience leading discovery projects
- Previous significant experience in processing of biologics and/or vaccines and GMP operations
8
Responsibilities For Associate Principal Scientist Bioprocess Formulation & Process Development Resume
- Previous experience leading work groups
- Experience in applying a variety of biochemical, biological, and immunological techniques (ELISA, cell-based assays, FACS, MSD, EnVision, ForteBio, etc.)
- Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment
- Experience in authoring of regulatory submissions
- Experience with analysis of data originating from clinical trials
- A strong academic record including publications in peer reviewed journals
- Experience in applying Quality by Design to process development
- Several years of relevant experience in drug discovery and/or early development or in a leading academic institution
9
Responsibilities For Associate Principal Scientist, Immuno Resume
- Maintain a strong, external scientific reputation for the S&CP department through publications & presentations
- Solid appreciation of commercial requirements
- Good knowledge of HACCP and ISO 22000
- Strong track record of working across boundaries to deliver common goals
- Develop validation strategies for improving disease relevant in vivo models
10
Responsibilities For Associate Principal Scientist Oncology Resume
- Be able to demonstrate successful technical transfer expertise, gained in a Biologics environment
- OR BS in Molecular Biology, Biochemistry, or related Biological Sciences with at least 10 years of cell line development experience in industry
- Ph.D with at least two years of experience in analytical chemistry, biochemistry, or a closely-related discipline
- Hands-on experience with key NGS bioinformatics tools (BWA, GATK etc) and with linux high performance environment (shell scripting, python)
- Experience with scientific programming (Perl, Python, Pipeline Pilot) and data analytics (e.g., Spotfire)
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