Senior Principal Scientist Resume Sample
Work Experience
- Experience in development and application of model-based meta-analyses
- Communicate internally and externally on topics related to Clinical Pharmacology, Pharmacometrics and Model-Based Meta-Analysis
- Keep up-to-date with and propose the implementation of scientific and technological developments in Pharmacometrics
- Experience with general statistical programming tools/languages such as R, Matlab, SAS, etc
- Interact as a pharmacometrics expert with matrix project teams consisting of experts from diverse functional areas
- Exercise independent intellectual judgement based on the individual’s specialized skills in pharmaceutical analysis
- Recent PhD Graduates with organic/analytical expertise welcome to apply
- Expertise desired in development of laser protection materials and devices against an agile laser threat or threats from multiple lasers with differing wavelengths
- Materials fabrication, materials characterization, non linear testing, device fabrication and concept generation experience required
- As a technical leader, the Senior Principal Scientist proactively seeks and leverages external relationships and partnerships to identify opportunities and to meet business needs. He/She provides leadership in strategic technical planning and shapes the business by translating insights into innovative and viable products or solutions, adding significant value
- Demonstrated knowledge in the areas of pharmacokinetics/bioanlaysis/immunogenicity and proven track record of scientific contributions and problem solving in the areas of preclinical and clinical biologics development
- Demonstrated experience in working with BA CROs and managing multiple projects and modalities
- Strategic thinker who can balance near term objectives with long term goals and outcomes
- Strong verbal and written communication skills; ability to clearly articulate scientific viewpoints to diverse audience. Team player with mentoring ability
- Work effectively in a collaborative team environment where results are achieved through persuasion
- Years of Experience:
- Advanced knowledge of regulatory, technical and standard industrial practices in bioanalysis for biologics/immunogenicity/pharmacokinetics and a broad knowledge base in drug discovery and development process
- In depth understanding of PBPK modeling software such as SimCYP and GastrPlus are a necessity
- Broad based understanding of in vitro and in vivo techniques used to characterize drug metabolism, pharmacokinetics and drug interactions potential of drug candidates
- Effective at working with interdisciplinary project teams, including helping to develop DMPK strategies and implement drug development plans
- Oversee studies performed internally or at external contract research laboratories
- Awareness of regulatory requirements in the areas of drug metabolism, drug-drug interactions, bioanalysis, toxicology, and clinical pharmacology
- Experience preparing drug metabolism reports and regulatory submission documents
- Strong written and verbal communication skills, and computer proficiency are required
- Effectively work with the wider Pharmaceutical R&D Group, Chemical Process Development Group, Analytical Development Group, and various Research Units to commercialize novel ideas relating to nanoparticle drug delivery
Education
Professional Skills
- Demonstrated knowledge in the areas of pharmacokinetics/bioanlaysis/immunogenicity and proven track record of scientific contributions and problem solving in the areas of preclinical and clinical biologics development. -
- Proven leadership and team building skills for leading technical programs and oversight based upon industry experience in positions of technical leadership
- Excellent influencing, negotiation and networking skills
- Excellent interpersonal and team skills; track record of success working collaboratively across disciplines
- Excellent instrument trouble shooting skills
- Strong consultative and partnering skills
- Strong verbal and written communication skills; ability to clearly articulate scientific viewpoints to diverse audience
How to write Senior Principal Scientist Resume
Senior Principal Scientist role is responsible for leadership, interpersonal, scientific, mentoring, accountability, independent, presentation, technology, analytical, manufacturing.
To write great resume for senior principal scientist job, your resume must include:
- Your contact information
- Work experience
- Education
- Skill listing
Contact Information For Senior Principal Scientist Resume
The section contact information is important in your senior principal scientist resume. The recruiter has to be able to contact you ASAP if they like to offer you the job. This is why you need to provide your:
- First and last name
- Telephone number
Work Experience in Your Senior Principal Scientist Resume
The section work experience is an essential part of your senior principal scientist resume. It’s the one thing the recruiter really cares about and pays the most attention to.
This section, however, is not just a list of your previous senior principal scientist responsibilities. It's meant to present you as a wholesome candidate by showcasing your relevant accomplishments and should be tailored specifically to the particular senior principal scientist position you're applying to.
The work experience section should be the detailed summary of your latest 3 or 4 positions.
Representative Senior Principal Scientist resume experience can include:
- Driving Results: Strong evidence for delivering on commitments, working-in and leading multi-disciplinary teams
- Demonstrated experience in working with BA CROs and managing multiple projects and modalities -
- Demonstrated experience applying computational approaches to deliver insights/hypotheses, e.g. multivariate, Bayesian and machine learning approaches
- Evidence of experience in developing assays for target identification and screening
- Demonstrated experience with managing multiple development projects in parallel, including key participation on multi-disciplinary project teams
- Effectively assessing the ideas both from the business and technical points of view
Education on a Senior Principal Scientist Resume
Make sure to make education a priority on your senior principal scientist resume. If you’ve been working for a few years and have a few solid positions to show, put your education after your senior principal scientist experience. For example, if you have a Ph.D in Neuroscience and a Master's in the same sphere, just list your Ph.D. Besides the doctorate, Master’s degrees go next, followed by Bachelor’s and finally, Associate’s degree.
Additional details to include:
- School you graduated from
- Major/ minor
- Year of graduation
- Location of school
These are the four additional pieces of information you should mention when listing your education on your resume.
Professional Skills in Senior Principal Scientist Resume
When listing skills on your senior principal scientist resume, remember always to be honest about your level of ability. Include the Skills section after experience.
Present the most important skills in your resume, there's a list of typical senior principal scientist skills:
- Demonstrated strong interpersonal and negotiating skills and leveraging of those competencies to ensure continuous progress
- Demonstrated strong and mature leadership and influencing skills
- Strong skills in providing technology guidance and colleague development through mentoring and coaching
- Effective written, interpersonal, and presentation skills, including managing technical discussions with internal and external clients
- Postdoctoral experience and at least 8 years additional experience in an industrial or academic setting, with experience in project management
- Experience and Skills - Knowledge of investigative and mechanistic toxicology of drugs
List of Typical Experience For a Senior Principal Scientist Resume
Experience For Senior / Principal Scientist Resume
- Excellent oral/written communication skills, providing proactive communications
- Working with local leadership to put in place an active program of self-development in medicinal chemistry design skills
- Demonstrates strong learning agility. Comfortable moving into and mastering new or unfamiliar areas of science
- Effectively creating technical solutions to achieve defined performance requirements
- Effectively communicates with managers on project status and solutions for problems encountered
- Exercise independent judgment based on the individual’s specialized skills in pharmaceutical analysis
- Participating in Evidence Based Design (EBD) acoustical case studies
Experience For Senior Principal Scientist, Immune Modulation Resume
- Demonstrates innovative thinking to meet in vitro screening needs, including use of iPSCs and 3D tissue structures
- Experience with managing a laboratory and directing the activities of more junior personnel
- Develop, technology transfer, and optimize continuous manufacturing processes for new solid dosage products and formulations
- Good working knowledge of the pharmaceutical industry and regulatory requirements
- Provides support to Tech. Ops Team for technology transfer to commercial manufacturing sites and process validation
- Proven capacity for innovative thinking
Experience For Senior Principal Scientist, Biotherapeutics Resume
- Track record of innovation in the field of biomarkers and precision medicine and in driving effective change
- Designing, planning, and executing the project plan / experiment/process, analyzing the data, recommending corrective solution, and reporting the results
- Partnering with marketing on white papers, presentations and articles highlighting the importance of acoustics
- Participating in Global EASE (Enhanced Acoustic Simulator for Engineers) modeling capabilities, developing new tools and applications
- Managing expansion and maintenance of existing Global acoustics software tools such as RT modeling
- Providing acoustic technical services to Global marketing & sales such as product literature and training programs
- Identifying and lobbying key government and NGO decision makers in building design & construction
Experience For Senior Principal Scientist, Process Research Resume
- Participating in the development of Global national and international standards (and codes) on building acoustics
- Utilizing historical knowledge in the field of rare muscle disease to prosecute external opportunities and supporting due diligence efforts
- Understanding of organic chemistry and chemical engineering principles
- Providing acoustic support for both sourced and internal new product development efforts
- Connecting new material technologies with business needs to identify high business impact opportunities
- Developing intellectual property for key innovations
Experience For Senior.principal Scientist Toxicologist Resume
- Performing a large variety of analytical tasks involved in extractables and leachables projects
- Interacting with key customer groups to understand market drivers and influence their decisions
- Stay current with systems biology technologies including those relating to genome-editing, chemical biology, and proteomics
- Drive fundamental understanding of unit operations through experimental investigation and modeling
- Daily operational oversight of Biomarker LC/MS group activities – full resource scheduling, project scheduling, timelines and deliverables, etc
- Exposure to the fundamental principles of continuous processing from a laboratory and manufacturing perspective
- Document and present development, manufacturing status and testing results as needed
- An understanding of Quality-by-Design principles and setting clinically relevant product specifications
- Keep up to date with emerging literature and science in the systems pharmacology modeling and simulation sciences
Experience For Senior / Principal Scientist Group Leader Resume
- Partnership with enabling functions across Pfizer, including drug safety, formulations and process chemistry to drive project advancement to the clinic
- Serve as the SME and point person for all things polymer—including materials, conjugations, and characterization
- Technology transfer of pre-clinical processes to manufacturing group
- Write and manage data acquisition and automation programs for manufacturing equipment skids
- Design and deliver novel solutions to challenging problems – a track record of innovation and publication
- Perform advanced data analysis, process model development, and apply findings to the continuous processing platform
Experience For Senior Principal Scientist for Process Technology Resume
- Communicate project requirements to vendors to obtain proposals for equipment installation of continuous manufacturing equipment
- Write technical reports and/or presentations relevant to drug product continuous processing activities and present to various levels of management
- Prepares, reviews and approves bids and proposals. Negotiates with client and business development on timelines and pricing
- Assist in the ongoing laboratory operations improvement and growth – processes, procedures, policies, etc
- Heavy customer facing interactions for R&D projects, biomarker selection, methodology selection, etc
- Assist in the contracts, proposals, development process & pricing
Experience For Senior Principal Scientist Pharmacokinetics Resume
- Familiarity with in-situ analytical tools (e.g FTIR, FBRM, and UV/Vis) and common analytical chemistry instrumentation including UPLC, HPLC, and MS
- Manage the cancer systems biology group and its screening projects, and direct associate personnel
- Influence disease Research Unit portfolios through delivery of screening results, follow-up studies, and associated insights
- Track record of innovative and impactful research including peer-reviewed publications, preferably with systems biology relevant methodologies
- Manages the generation of data, expertly analyzes and interprets experimental data ensuring its accuracy, and delivers such to the project in a timely manner
- Builds the capacity/functionality of the Tumor Biology group ensuring the latest methodology/ technology is considered and adopted as necessary
- Support drug substance and drug product impurity characterization and identification using NMR, LC/MS, and preparative chromatography purification
- Oversee propellant development, characterization and manufacturing
Experience For Senior Principal Scientist Biostatistician Resume
- Serve as an R&D Laboratory liaison between IPTs and Manufacturing
- Develops strategies for establishing bioequivalence for drug products in development and occasionally provides support for marketed products
- Sound understanding of drug product development process, from pre-formulation and prototype development through process scale-up
- Track record of successfully applying high-level scientific judgment in a variety of complex and unprecedented situations
- Basic understanding of Multiple Myeloma and/or other heme malignancies
- Manage a lab and pilot plant for scale up work and process development
- Manage a group of scientists (supervise up to 10 colleagues) within the Analytical Development group within Vaccine Research and Development, which has a focus on supporting the analytical and antibody-based bioassay development and analysis of various antigens (including viruses, proteins, and conjugates) used in vaccines under development
Experience For Senior Principal Scientist, Chemistry Resume
- Review design and oversee development, qualification and transfer of assays for testing/characterization of intermediate, in-process, DS, formulated or final fill vaccine samples Primary methodologies include separation-based techniques, mass spectrometry, and antibody-based bioassay-based techniques
- Collaborate as necessary with appropriate leaders/scientists within Vaccines and across other departments
- Plan, coordinate and support resources to ensure the timely execution of the analysis of intermediate, in-process, formulated, or final fill vaccine samples for samples used in support of planned Toxicology studies
- Write and review technical documents to support assay development, qualification, and transfer
- Closely work with management to define long term strategies for Analytical and Formulation Development. Represent Analytical and Formulation Development in project team meetings
- Satisfactorily completes all GLP and safety training in conformance with departmental requirements. Where applicable, performs job responsibilities in compliance with GLP and all other regulatory agency requirements
List of Typical Skills For a Senior Principal Scientist Resume
Skills For Senior / Principal Scientist Resume
- Good listening skills and strong interpersonal skills who can work effectively with people of diverse rank and culture across a variety of business disciplines
- Good leadership and management skills/experience
- Previous experience in an analytical testing laboratory that provides the knowledge, skills, and abilities to perform the job (comparable to 15+ years)
- Learn new areas of biological sciences and build on solid foundation of quantitative skills to develop mechanistically-relevant PK-PD models
- Good listener and ability to effectively interact with colleagues with a variety of backgrounds
- Experience people management experience (supervising, coaching, mentoring) is required
- Strong external network and experience in developing industrial and academic partners in relevant technical areas
- Work effectively in a collaborative team environment where results are achieved through persuasion
Skills For Senior Principal Scientist, Immune Modulation Resume
- Demonstrated experience in design, execution and interpretation of in vivo and/or in vitro biological experiments
- Solid experience in working with models that characterize adaptive immune responses especially in the tumor microenvironment
- Self-motivated and able to acquire new knowledge and skills in both scientific and business arenas
- PhD and 2+ years of productive, relevant work or postdoctoral experience or MS and 5+ years of productive, relevant work experience
- Experience with Matlab is strongly recommended
- Proven track record of designing, leading, and managing complex computational research projects
- Thorough understanding of development processes in R&D and good understanding of development activities in some functions external to R&D
Skills For Senior Principal Scientist, Biotherapeutics Resume
- BS or MS in Biological Sciences/Chemical Engineering/Biological Engineering/Chemistry with 18 years relevant experience
- Experience working in a Biopharmaceutical company developing drug development candidates in the preclinical space
- Experience with outsourcing and/or contract manufacturing
- Strong record of pre-clinical drug discovery including moving scientific targets into early clinical development
- Experience contributing to regulatory submissions including IND, BLA, and MAA is required
- Experience with modeling tools and techniques, such as PBPK modeling
- A demonstrated capability to build mechanistic models for predicting exposure following oral and other routes of delivery
- Pharmaceutically relevant experience or formal training in computational chemistry/biology, computer science or medicine
- In electronic materials experience in advanced wet-etching chemicals used in semiconductor processes
Skills For Senior Principal Scientist, Process Research Resume
- Experience working with models of human disease is highly desirable
- Previous experience in managing a scientist(s)
- Knowledge of and experience working with skeletal and cardiac muscle cells and tissues
- Demonstrated aptitude for independent research and innovative thinking
- Experience in chemical process development or manufacturing
- Management experience with personnel, projects, and outsourcing
Skills For Senior.principal Scientist Toxicologist Resume
- Experience managing a team of scientist or engineers
- Experience in scaling up pharmaceutical processes
- Experience preparing batch records, lab reports, SOPs, and other cGMP documentation
- Working experience in biotech / pharma industry
- Strong belief that modeling and simulation can have a significant positive impact on research projects
- Experience leading a medicinal chemistry team
- Has a strong sense for urgency and brings a creative approach to problem solving
- PhD in molecular biology or related field, with significant experience and expertise in 3D culturing of cancer cells and organoid technology
Skills For Senior / Principal Scientist Group Leader Resume
- Applied experience in modern control theory, process modeling, and systems optimization
- Experience with mathematical modeling and optimization software to solve practical problems
- In-depth experience in the care and use (to include environmental enrichment and training) of nonhuman primates
- Experienced in using LC/MS/MS techniques for structural elucidation
- Experience is authoring bio-waiver justifications for sterile and non-sterile products
- Experience in performing pharmacological and mechanistic studies in models of cardiovascular, liver, metabolic and/or kidney diseases is required
Skills For Senior Principal Scientist for Process Technology Resume
- Academic background in Analytical Chemistry or a related chemistry discipline (e.g. Physical, Organic) with demonstrated analytical capabilities
- Demonstrates cross-functional scientific knowledge
- Has demonstrated the ability to have a positive impact on others
- Direct experience with the phases of drug discovery and development, with particular emphasis on compound selection and translational research issues
- Good team player and communicator that can work well with geographically distributed teams
- Postdoctoral experience is required
- Industry experience in biochemical and cell-based assay development in an HTS or in vitro pharmacology group is required
- Track record of accomplishment in the pharmaceutical industry, as demonstrated by publications, presentations and/or patent applications
- Build strong rapport with colleagues, customers and external partners
Skills For Senior Principal Scientist Pharmacokinetics Resume
- Strong Chemistry and/or Toxicology background
- Demonstrated leadership, management and mentorship ability
- Experience with implementation of industrial model-based process control & optimization is required
- API experience in the pharmaceutical industry required
- Process chemistry experience in a GMP environment required
Skills For Senior Principal Scientist Biostatistician Resume
- Standing, sitting, bending, lifting, walking in a laboratory or vivarium setting
- Developing and/or expanding one’s own scientific expertise as well as enhancing and advancing the expertise of those reporting to him/her
- Identifying and supporting Global university research on building acoustics and human performance
- Working knowledge of organic and/or physical organic chemistry and chemical engineering principles
- Creating and documenting intellectual property in invention disclosures, patent applications and technical reports
- Driving for continuous improvement
- Understanding of key concepts from relevant partner disciplines included Pharmacology, ADME, Pharmaceutical Sciences and Drug Safety
- Understanding of chemical mechanisms, e.g. formation of reactive metabolites
Skills For Senior Principal Scientist, Chemistry Resume
- Educating architects, interior design professionals, government & academic groups, technical societies and associations
- Working with project teams defines study aims and experimental plans that meet the objectives of the research plan
- Identifying opportunities, followed by chemistry ideation and hands-on development in close collaboration with application research
- Assessing initial technical and economic feasibility
- Presenting scientific accomplishments internally and externally to the scientific community and discussed with key opinion leaders
- Working knowledge of UPLC, MS, and NMR spectroscopy
- Consulting with engineers, scientists, program and project managers
- Presenting to customers, program managers, management and design teams
- Assessing reliability, probability, and technical decisions based on statistical methods
List of Typical Responsibilities For a Senior Principal Scientist Resume
Responsibilities For Senior / Principal Scientist Resume
- Demonstrated capacity for robust and innovative problem solving skills
- Effective talent management and mentoring skills, with an ability to positively motivate others
- Collaboration: Strong evidence for delivering on commitments, working-in and leading multi-disciplinary teams
- Expand self-awareness and develop leadership skills as defined; attend applicable leadership training based on identified needs
- Proven highly relevant experience in Upstream or Downstream Bioprocessing
- Experience managing a solid-state lab
- Experience managing or mentoring groups of 10+ scientists
- Experience writing and reviewing regulatory filings in support of novel drg products
Responsibilities For Senior Principal Scientist, Immune Modulation Resume
- Experience in problem solving for non-clinical toxicological issues and developing assays to “de-risk” compounds
- Several years of experience in the pharmaceutical industry with a sound understanding and track record especially in cardiovascular and /or renal pharmacology
- In-depth expertise and demonstrated success in using translational based approaches to advance immune and inflammatory focused drug discovery projects
- Excellent communication and writing proficiencies
- Experience building scientific organizations through recruitment and development
Responsibilities For Senior Principal Scientist, Biotherapeutics Resume
- MSc, or PhD in Biochemistry, Biotechnology, chemical or biochemical engineering, or a related discipline with at least 5 years of experience in DSP operations
- Demonstrated track record in developing robust, scalable, purification processes for monoclonal antibodies and/or recombinant proteins
- Experience in an industrial research lab leading teams with 5 or more members
- Experience in applying innovative tools such PAT for cell culture process development and characterization
- Demonstrate a broad understanding of the end-to-end drug and diagnostic development process
- Demonstrated success in working with cross-functional scientific and business environments
- Experience providing technical oversight to other laboratory scientist
- Experience developing methods for protein quantitation by mass spectrometry
Responsibilities For Senior Principal Scientist, Process Research Resume
- Experience characterizing nucleotide based products
- Existing networks in the field of diabetes, Cardiovascular and Kidney are of advantage
- Understanding of the perspectives of a variety of stakeholders (e.g., payers, governments, policy-makers, physicians and patients) over multiple geographies
- Working knowledge of statistical methods for DOE design and data analysis (e.g., JMP or Design Expert software)
- Keen to interact as a modeling and simulation expert with matrix project teams working closely with departmental, Biology and Clinical scientists
- Contribute to other activities within Screening beyond Compound Profiling
Responsibilities For Senior.principal Scientist Toxicologist Resume
- The job requires standing and walking on a daily basis
- Keen to interact as a modeling and simulation expert with matrix project teams working closely with PDM, Biology and Clinical scientists
- Strategically applying functional area knowledge to frame critical drug development questions for optimizing model-based drug development
- Agility: Have confidence dealing with uncertainty and working outside scientific comfort zone
- Standard laboratory conditions – sitting, standing, primarily lab based
Responsibilities For Senior / Principal Scientist Group Leader Resume
- Critically assessing current trends and upcoming techniques for current and future applications
- Supervise others in performing client’s service requirements
- Participate Preclinical Safety Department activities (staff meeting, scientific forums, etc.), and special projects
- Willingness to interact globally with colleagues in Germany, Austria and the USA including occasional travel to global research sites
- Displays sound scientific judgment and is willing and able to defend new ideas against critique
- Keep up-to-date with and propose the implementation of scientific and technological developments in the area of PKPD modeling and simulation
- Deliver computational analyses of high-dimensional datasets from model systems, molecular profiling data through the translation of bioinformatics data
- Knowledge of chemical/process engineering principles
Responsibilities For Senior Principal Scientist for Process Technology Resume
- Knowledge of analytical instrumentation, particularly particle sizing and HPLC
- Work in a laboratory environment performing experiments in a laboratory fume hood and perform complex data analysis
- Ph.D. in Organic Chemistry, Biochemistry or Chemical Engineering
- Track record of new product development and optimization based on optimizing structure-activity relationships
- Thorough understanding of the basic principles of pharmacokinetics (non-compartmental, compartmental, PBPK)
- Translate/condense/summarize outcomes of modeling and simulation analyses into information that can be used by project teams
- Keep up-to-date with and propose the implementation of scientific and technological developments in the area of PK-PD modeling and simulation
- Motivated to develop a career as a hands-on, technical modeling and simulation expert in a preclinical drug discovery environment
Responsibilities For Senior Principal Scientist Pharmacokinetics Resume
- Acts as a resource to peers in developing new, innovative approaches to experimental design
- Independently (or using collaborations) develop scientific direction for assignments
- Has a genuine passion for science and operations and personal determination for excellence and for finding new ways to perform his/her job better
- Deep knowledge in APC-T cell biology, tolerance, T cell signaling and innate immunity
- Guide and advise during implementation of new methodologies and processes
- In upstream and/or downstream bioprocessing
- Identify off-site contract testing needs
- Result oriented; quality work provided even when operating under tight timelines and budgets
- Team player with mentoring ability. -
Responsibilities For Senior Principal Scientist Biostatistician Resume
- Strategic thinking, judgment, and business acumen
- Proficiency in specialized software packages is desirable, e.g. WinNonlin, GastroPlus, MATLAB
- The ability to communicate effectively orally and in writing in an interdisciplinary environment is essential. Honed coaching and negotiating skills are also highly desirable
- Develops cross functional strategies
- Held accountable for cross functional strategies
- Make recommendations to Senior Management and larger scientific community
- Guide/mentor/develop others in broad area of influence
- Perform work for both routine and non-routine work as specified by separate and applicable technical job description for individual
Responsibilities For Senior Principal Scientist, Chemistry Resume
- Foster motivation and morale
- Monitor and approve employees’ time worked through time-entry system
- Strive for continuous improvement by streamlining existing workflows in order to increase the volume of CLD work performed by the function while identifying opportunities to shorten the timelines for stable cell generation
- Develop constructive working relationships in both internal and external networks for the purpose to strengthen the CLD function and to align team goals with organizational objectives
- To provide leadership to direct reports through pro-active performance management, mentoring and coaching
- Coordinate research efforts and make key technical contributions affecting the direction of the group and/or project
- Provide and promote support for operational excellence according to Sanofi values and ethics
- Lead drug discovery project teams working with scientific platform teams and champion projects from discovery into early clinical development